

For this, you’ll need to have Outlook pinned to your Taskbar. Many users have claimed that the “Set of folders cannot open Outlook” error can be avoided if you start Outlook from the Taskbar. Restart the MS Outlook app and if it opens up without any errors, it confirms that the previous profile had been corrupted.Now from the section that says “When starting Outlook, use this profile,” choose the new profile from the drop-down menu that says “Always use this profile.” Click the OK button.Once your profile has been created, it will come up in the General tab in the Mail dialog box.Go to the “Auto Account Setup” window and enter the details of your email account.Click on “Show Profiles” and a new wizard will show up.Open Control Panel and click on “Mail (MS Outlook 2016)”.In this case, attempt creating a new Outlook profile:

gets corrupted, then you could get the error “The set of folders cannot be opened” error. Your Outlook profile contains all your Outlook settings. If you are still facing the same error, move on to the next solutions. Restart your Outlook service and check if this error goes away or not.Deselect all the entries in the list and click the “OK” A list of all the Add-ins will show up.Enter “Outlook/safe” in the given field of Run utility and press the OK button.

Press the Windows + R keys to open up the Run utility.Given below are the steps you need to follow:

whether the issue is caused by the Outlook application itself or its add-ins. Launching the Microsoft Outlook app in safe mode will let you know the source of the problem, i.e.
